The Vertical HE Mouse has a 70°vertical grip which provides a neutral, relaxed position of the hand and wrist. You move from the forearm instead of your wrist, which fights RSI. The mouse fits comfortably in your hand, and supports your wrist and fingers. In standard size Vertical HE 70° comes right and left handed and wired and wireless. Also sized for the larger hand in right hand only wired and wireless. 4 buttons and scroll wheel on every model. Buttons can be customised to your personal needs. Large model has DPI switch and speed guide on the face.